Summary

Name CEP72
Full Name Centrosomal protein of 72 kDa
Synonyms Cep72 | KIAA1519
Primary ID Q9P209
Links - -
Type protein
Relations 1
Function Involved in the recruitment of key centrosomal proteins to the centrosome. Provides centrosomal microtubule-nucleation activity on the gamma-tubulin ring complexes (gamma-TuRCs) and has critical roles in forming a focused bipolar spindle, which is needed for proper tension generation between sister chromatids. Required for localization of KIZ, AKAP9 and gamma-tubulin ring complexes (gamma-TuRCs) (PubMed:19536135). Involved in centriole duplication. Required for CDK5RAP22, CEP152, WDR62 and CEP63 centrosomal localization and promotes the centrosomal localization of CDK2 (PubMed:26297806).

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Relations

Regulator Mechanism target score ℹ
+ CEP72up-regulates activity img/direct-activation.png relocalization CDK5RAP2 0.65
Publications: 1 Organism: Homo Sapiens