Summary

Name KLHL8
Full Name Kelch-like protein 8
Synonyms | KIAA1378
Primary ID Q9P2G9
Links - -
Type protein
Relations 2
Function Substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin ligase complex required for The BCR(KLHL8) ubiquitin ligase complex mediates ubiquitination and degradation of RAPSN. {ECO:0000269|PubMed:19158078}.

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Relations

Regulator Mechanism target score
+ down-regulates quantity by destabilization img/direct_inhibition.png binding RAPSN 0.496
Publications: 1 Organism: Mus Musculus
+ up-regulates activity img/direct-activation.png binding Cullin 3-RBX1-Skp1 0.412
Publications: 1 Organism: Mus Musculus