Summary

Name TNFRSF10D
Full Name Tumor necrosis factor receptor superfamily member 10D
Synonyms Decoy receptor 2, DcR2, TNF-related apoptosis-inducing ligand receptor 4, TRAIL receptor 4, TRAIL-R4, TRAIL receptor with a truncated death domain | DCR2, TRAILR4, TRUNDD
Primary ID Q9UBN6
Links - -
Type protein
Relations 1
Function Receptor for the cytotoxic ligand TRAIL. Contains a truncated death domain and hence is not capable of inducing apoptosis but protects against TRAIL-mediated apoptosis. Reports are contradictory with regards to its ability to induce the NF-kappa-B pathway. According to PubMed:9382840, it cannot but according to PubMed:9430226, it can induce the NF-kappa-B pathway.

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Relations

Regulator Mechanism target score
+ down-regulates img/direct_inhibition.png binding TNFSF10 0.718
Publications: 1 Organism: Homo Sapiens