Identifier |
Residue |
Sequence |
Organism |
Cell Line |
SIGNOR-261348 |
|
|
Homo sapiens |
HEK-293 Cell |
pmid |
sentence |
28827405 |
FAM8A1 enhances binding of Herp to Hrd1, an interaction that is required for ERAD. Our findings support a model of Hrd1 complex formation, where the Hrd1 cytoplasmic domain and FAM8A1 have a central role in the assembly and activity of this ERAD machinery. A conserved Hrd1 cytoplasmic domain interacts with FAM8A1 and Herp |
|