Summary

Name FBXL17
Full Name F-box/LRR-repeat protein 17
Synonyms F-box and leucine-rich repeat protein 17, F-box only protein 13 | FBL17, FBX13, FBXO13
Primary ID Q9UF56
Links - -
Type protein
Relations 1
Function Substrate-recognition component of the SCF(FBXL17) E3 ubiquitin ligase complex, a key component of a quality control pathway required to ensure functional dimerization of BTB domain-containing proteins (dimerization quality control, DQC) (PubMed:30190310). FBXL17 specifically recognizes and binds a conserved degron of non-consecutive residues present at the interface of BTB dimers of aberrant composition

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Relations

Regulator Mechanism target score
+ down-regulates quantity by destabilization img/direct_inhibition.png ubiquitination SUFU 0.432
Publications: 1