Identifier |
Residue |
Sequence |
Organism |
Cell Line |
SIGNOR-253545 |
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pmid |
sentence |
27234298 |
Here, we show that Fbxl17 (F-box and leucine-rich repeat protein 17) targets Sufu for proteolysis in the nucleus. The ubiquitylation of Sufu, mediated by Fbxl17, allows the release of Gli1 from Sufu for proper Hh signal transduction |
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