3.0
Summary
| Name |  PARP2
|
| Full Name | Poly [ADP-ribose] polymerase 2 |
| Synonyms | PARP-2, hPARP-2, ADP-ribosyltransferase diphtheria toxin-like 2, ARTD2, NAD(+) ADP-ribosyltransferase 2, ADPRT-2, Poly[ADP-ribose] synthase 2, pADPRT-2 | ADPRT2, ADPRTL2 |
| Primary ID | Q9UGN5 |
| Links |  -  -  |
| Type | protein |
| Relations | 4 |
| Inhibitors | 1038915-60-4; olaparib; A-966492; veliparib |
| Function | Poly-ADP-ribosyltransferase that mediates poly-ADP-ribosylation of proteins and plays a key role in DNA repair (PubMed:10364231, PubMed:25043379, PubMed:27471034, PubMed:32028527, PubMed:32939087). Mediates glutamate, aspartate or serine ADP-ribosylation of proteins |
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Relations
| Regulator | Mechanism | target | score ℹ | |
|---|---|---|---|---|
| + | 1038915-60-4 | down-regulates 
chemical inhibition
|
PARP2 | 0.8 |
| Publications: | 1 | Organism: | Homo Sapiens | |
| + | olaparib | down-regulates
chemical inhibition
|
PARP2 | 0.8 |
| Publications: | 1 | Organism: | Homo Sapiens | |
| + | A-966492 | down-regulates
chemical inhibition
|
PARP2 | 0.8 |
| Publications: | 1 | Organism: | Homo Sapiens | |
| + | veliparib | down-regulates
chemical inhibition
|
PARP2 | 0.8 |
| Publications: | 1 | Organism: | Homo Sapiens | |