4.0
Summary
| Name |  MLX
|
| Full Name | Max-like protein X |
| Synonyms | Class D basic helix-loop-helix protein 13, bHLHd13, Max-like bHLHZip protein, Protein BigMax, Transcription factor-like protein 4 | BHLHD13, TCFL4 |
| Primary ID | Q9UH92 |
| Links |  -  -  |
| Type | protein |
| Relations | 1 |
| Function | Transcription regulator. Forms a sequence-specific DNA-binding protein complex with MAD1, MAD4, MNT, WBSCR14 and MLXIP which recognizes the core sequence 5'-CACGTG-3'. The TCFL4-MAD1, TCFL4-MAD4, TCFL4-WBSCR14 complexes are transcriptional repressors. Plays a role in transcriptional activation of glycolytic target genes. Involved in glucose-responsive gene regulation. |
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Relations
| Regulator | Mechanism | target | score ℹ | |
|---|---|---|---|---|
| + | MLX | form complex 
binding
|
MLXIP-MLX transcription factor complex | 0.669 |
| Publications: | 1 | Organism: | Homo Sapiens | |