3.0
Summary
| Name |  GTF2IRD1
|
| Full Name | General transcription factor II-I repeat domain-containing protein 1 |
| Synonyms | GTF2I repeat domain-containing protein 1, General transcription factor III, MusTRD1/BEN, Muscle TFII-I repeat domain-containing protein 1, Slow-muscle-fiber enhancer-binding protein, USE B1-binding protein, Williams-Beuren syndrome chromosomal region 11 protein, Williams-Beuren syndrome chromosomal region 12 protein | CREAM1, GTF3, MUSTRD1, RBAP2, WBSCR11, WBSCR12 |
| Primary ID | Q9UHL9 |
| Links |  -  -  |
| Type | protein |
| Relations | 1 |
| Function | May be a transcription regulator involved in cell-cycle progression and skeletal muscle differentiation. May repress GTF2I transcriptional functions, by preventing its nuclear residency, or by inhibiting its transcriptional activation. May contribute to slow-twitch fiber type specificity during myogenesis and in regenerating muscles. Binds troponin I slow-muscle fiber enhancer (USE B1). Binds specifically and with high affinity to the EFG sequences derived from the early enhancer of HOXC8 (By similarity). |
