Summary

Name ANAPC2
Full Name Anaphase-promoting complex subunit 2
Synonyms APC2, Cyclosome subunit 2 | APC2, KIAA1406
Primary ID Q9UJX6
Links - -
Type protein
Relations 3
Function Together with the RING-H2 protein ANAPC11, constitutes the catalytic component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. The APC/C complex acts by mediating ubiquitination and subsequent degradation of target proteins

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Relations

Regulator Mechanism target score
+ down-regulates img/direct_inhibition.png binding DVL1 0.241
Publications: 1 Organism: Homo Sapiens
+ form complex img/form-complex.png binding APC-c 0.868
Publications: 1
+ up-regulates activity img/direct-activation.png neddylation ANAPC2 0.373
Publications: 1 Organism: Homo Sapiens