+ |
RPS6KA6 | up-regulates activity
phosphorylation
|
RPS6KA6 |
0.2 |
Identifier |
Residue |
Sequence |
Organism |
Cell Line |
SIGNOR-275797 |
Ser232 |
DQEKKAYsFCGTVEY |
|
|
pmid |
sentence |
15632195 |
These mutants had minimal kinase activity and showed profoundly decreased phosphorylation at Ser232 compared with wild-type RSK4 (Fig 10B), suggesting that RSK4 can autophosphorylate at Ser232. |
|
Publications: |
1 |
+ |
RPS6KA6 | down-regulates activity
phosphorylation
|
EP300 |
0.255 |
Identifier |
Residue |
Sequence |
Organism |
Cell Line |
SIGNOR-275796 |
Ser89 |
SELLRSGsSPNLNMG |
|
|
pmid |
sentence |
34261798 |
Figure 2G shows that Ser89 phosphorylation of p300, an event that inhibits p300’s acetyltransferase activity (13), was decreased in RSK4-silenced A549 and T24 cells. Consequently, RSK4 may regulate the activity of the NFκB pathway by direct phosphorylation of p300, as recombinant RSK4 phosphorylates p300 on Ser89 in vitro |
|
Publications: |
1 |
+ |
RPS6KA6 | down-regulates activity
phosphorylation
|
GSK3B |
0.2 |
Identifier |
Residue |
Sequence |
Organism |
Cell Line |
SIGNOR-275801 |
Ser9 |
SGRPRTTsFAESCKP |
|
|
pmid |
sentence |
32396532 |
Moreover, RSK4 stabilized Beta-catenin in the presence of GSK-3Beta WT but not RSK4 stabilizes Beta-catenin through phosphorylation of GSK-3Beta (Ser9) in ESCC cells|GSK-3Beta S9A in ESCC cells, which was similar to overexpression of GSK3Beta S9D| |
|
Publications: |
1 |