| + |
PPP1R9A | up-regulates 
|
F-actin_assembly |
0.7 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-269180 |
|
|
Mus musculus |
Neuro-2a Cell |
| pmid |
sentence |
| 15996550 |
Neurabin and spinophilin are preferentially expressed in neurons, where they are highly localized to dendritic spines via an interaction with F-actin. The results obtained in the present study suggest a mechanism by which neurabin or spinophilin contributes to the organization of the F-actin cytoskeleton in dendritic spines, and in turn to the regulation of spine morphology, via the activity-dependent recruitment of the Rho-specific GEF Lfc |
|
| Publications: |
1 |
Organism: |
Mus Musculus |
| + |
PPP1R9A | up-regulates activity 
binding
|
ARHGEF2 |
0.347 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-269177 |
|
|
Mus musculus |
Neuro-2a Cell |
| pmid |
sentence |
| 15996550 |
The Rho Family GEF Lfc Interacts with Neurabin and Spinophilin. Neurabin and spinophilin are homologous protein phosphatase 1 and actin binding proteins that regulate dendritic spine function. The results obtained in the present study suggest a mechanism by which neurabin or spinophilin contributes to the organization of the F-actin cytoskeleton in dendritic spines, and in turn to the regulation of spine morphology, via the activity-dependent recruitment of the Rho-specific GEF Lfc |
|
| Publications: |
1 |
Organism: |
Mus Musculus |
3.0
PPP1R9A
- 
- 