3.0
Summary
| Name |  MAFF
|
| Full Name | Transcription factor MafF |
| Synonyms | U-Maf, V-maf musculoaponeurotic fibrosarcoma oncogene homolog F |
| Primary ID | Q9ULX9 |
| Links |  -  -  |
| Type | protein |
| Relations | 2 |
| Function | Since they lack a putative transactivation domain, the small Mafs behave as transcriptional repressors when they dimerize among themselves (PubMed:8932385). However, they seem to serve as transcriptional activators by dimerizing with other (usually larger) basic-zipper proteins, such as NFE2L1/NRF1, and recruiting them to specific DNA-binding sites. Interacts with the upstream promoter region of the oxytocin receptor gene (PubMed:8932385, PubMed:16549056). May be a transcriptional enhancer in the up-regulation of the oxytocin receptor gene at parturition (PubMed:10527846). |
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