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Summary
Name
SLC7A11
View Modifications
Full Name
Cystine/glutamate transporter
Synonyms
Amino acid transport system xc-, Calcium channel blocker resistance protein CCBR1, Solute carrier family 7 member 11, xCT |
Primary ID
Q9UPY5
Links
-
-
Type
protein
Relations
1
Function
Sodium-independent, high-affinity exchange of anionic amino acids with high specificity for anionic form of cystine and glutamate.
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by mechanism
none
phosphorylation
by effect
none
down-regulates activity
by organism:
none
Homo sapiens
by tissue:
none
by cell-line
none
U-87MG cell
▶
Modifications Tables
SLC7A11 as Target
Residue
Sequence
Modifier
Effect
Modification
Ser26
NVNGRLPsLGNKEPP
mTORC2
inhibition
phosphorylation
Relations
Regulator
Mechanism
target
score
ℹ
+
mTORC2
down-regulates activity
phosphorylation
SLC7A11
0.279
Identifier
Residue
Sequence
Organism
Cell Line
SIGNOR-273682
Ser26
NVNGRLPsLGNKEPP
Homo sapiens
U-87MG Cell
pmid
sentence
28648777
MTORC2 phosphorylates serine 26 at the cytosolic N terminus of xCT, inhibiting its activity.
Publications:
1
Organism:
Homo Sapiens