+ |
TOM40 complex | down-regulates activity
relocalization
|
ATF5 |
0.2 |
Identifier |
Residue |
Sequence |
Organism |
Cell Line |
SIGNOR-267685 |
|
|
|
|
pmid |
sentence |
31387448 |
Central to the mtUPR is the transcription factor ATF5. When stress causes protein import and/or electron transport chain dysfunction ATF5 accumulates in the nucleus to transcribe mitochondrial chaperones and protease genes |Under normal conditions, ATF5 is imported into and sequestered within mitochondria. |
|
Publications: |
1 |
+ |
ATF5 | up-regulates quantity by expression
transcriptional regulation
|
CYP2B6 |
0.2 |
Identifier |
Residue |
Sequence |
Organism |
Cell Line |
SIGNOR-253751 |
|
|
Homo sapiens |
|
pmid |
sentence |
18332083 |
We induced endoplasmic reticulum stress by means of amino acid limitation or selective chemicals, and assessed the time course response of ATF5 and CYP2B6. We found a post-transcriptional up-regulation of ATF5 and a parallel induction of CYP2B6 mRNA. |
|
Publications: |
1 |
Organism: |
Homo Sapiens |