Summary

Name MAP3K2
Full Name Mitogen-activated protein kinase kinase kinase 2
Synonyms MAPK/ERK kinase kinase 2, MEK kinase 2, MEKK 2 | MAPKKK2, MEKK2
Primary ID Q9Y2U5
Links - -
Type protein
Relations 5
Function Component of a protein kinase signal transduction cascade. Regulates the JNK and ERK5 pathways by phosphorylating and activating MAP2K5 and MAP2K7 (By similarity). Plays a role in caveolae kiss-and-run dynamics.

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Relations

Regulator Mechanism target score ℹ
+ MAP3K2up-regulates img/indirect-activation.png MAP2K5 0.751
Publications: 1 Organism: Homo Sapiens
+ MAP3K2up-regulates img/direct-activation.png phosphorylation MEK1/2 0.424
Publications: 1 Organism: Homo Sapiens
+ MAP3K2up-regulates img/direct-activation.png phosphorylation MAP2K5 0.751
Publications: 1 Organism: Homo Sapiens
+ MAP3K2up-regulates img/direct-activation.png phosphorylation MAP2K1 0.424
Publications: 1 Organism: Homo Sapiens
+ MAP3K2up-regulates activity img/direct-activation.png phosphorylation MAP2K4 0.594
Publications: 1 Organism: Homo Sapiens