+ |
NR2E3 | up-regulates quantity by expression
transcriptional regulation
|
ESR1 |
0.253 |
Identifier |
Residue |
Sequence |
Organism |
Cell Line |
SIGNOR-266207 |
|
|
Homo sapiens |
MCF-7 Cell |
pmid |
sentence |
22174013 |
NR2E3 directly regulates expression of ESR1 | Furthermore, overexpression of exogenous NR2E3 further increased expression of ESR1 and its downstream targets as well as its transcriptional activity in MCF-7 cells (Fig S1 of Supporting Information), strongly demonstrating that NR2E3 regulates ESR1 expression and subsequent ESR1-mediated induction of target genes. |
|
Publications: |
1 |
Organism: |
Homo Sapiens |
+ |
NR2E3 | up-regulates
binding
|
NR1D1 |
0.408 |
Identifier |
Residue |
Sequence |
Organism |
Cell Line |
SIGNOR-125661 |
|
|
Homo sapiens |
|
pmid |
sentence |
15190009 |
All four proteins, nr2e3, nr1d1, nrl and crx, could be co-immunoprecipitated from the bovine retinal nuclear extract, suggesting their existence in a multi-protein transcriptional regulatory complex in vivo. |
|
Publications: |
1 |
Organism: |
Homo Sapiens |
+ |
NR1D1 | up-regulates
|
NR2E3 |
0.408 |
Identifier |
Residue |
Sequence |
Organism |
Cell Line |
SIGNOR-125658 |
|
|
Homo sapiens |
|
pmid |
sentence |
15190009 |
Our results show that nr1d1 (rev-erb?) Also functions as a transcriptional activator of rod genes in the presence of nr2e3 |
|
Publications: |
1 |
Organism: |
Homo Sapiens |