Relation Results

Summary

Name LRRFIP2
Full Name Leucine-rich repeat flightless-interacting protein 2
Synonyms LRR FLII-interacting protein 2
Primary ID Q9Y608
Links - -
Type protein
Relations 1
Function May function as activator of the canonical Wnt signaling pathway, in association with DVL3, upstream of CTNNB1/beta-catenin. Positively regulates Toll ...
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Type: Score: Layout: SPV 
0.388LRRFIP2DVL3

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Relations
Regulator
Mechanism
target
score ℹ
+ LRRFIP2up-regulates img/direct-activation.png binding DVL3 0.388
Identifier Residue Sequence Organism Cell Line
SIGNOR-133429 Homo sapiens
pmid sentence
In particular, a previously unrecognized activator, lrrfip2 (leucine-rich repeat in flightless interaction protein 2), was found that interacts with dvl to increase the cellular levels of _-catenin and activate _-catenin/lef/tcf-dependent transcriptional activity
Publications: 1 Organism: Homo Sapiens
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