Relation Results

Summary

Name DYNC1LI1
Full Name Cytoplasmic dynein 1 light intermediate chain 1
Synonyms LIC1, Dynein light chain A, DLC-A, Dynein light intermediate chain 1, cytosolic | DNCLI1
Primary ID Q9Y6G9
Links - -
Type protein
Relations 1
Function Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to car ...
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Type: Score: Layout: SPV 
0.254MAPK1DYNC1LI1

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▶Modifications Tables

Relations
Regulator
Mechanism
target
score ℹ
+ MAPK1 img/unknown.png phosphorylation DYNC1LI1 0.254
Identifier Residue Sequence Organism Cell Line
SIGNOR-262773 Ser516 VSPTTPTsPTEGEAS Mus musculus NIH-3T3 Cell
pmid sentence
We have optimized a chemical genetic system using analog-sensitive ERK2, a form of ERK2 engineered to use an analog of adenosine 5'-triphosphate (ATP), to tag and isolate ERK2 substrates in vitro. This approach identified 80 proteins phosphorylated by ERK2, 13 of which are known ERK2 substrates. With this improved methodology, we detected 98 sites directly phosphorylated by ERK2 on 80 proteins from NIH 3T3-L1 fibroblasts. Thirteen of these proteins are known substrates and the rest represent previously unknown kinase/substrate interactions. (table1)
Publications: 1 Organism: Mus Musculus
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