3.0
Summary
| Name |  KCNE3View Modifications |
| Full Name | Potassium voltage-gated channel subfamily E member 3 |
| Synonyms | MinK-related peptide 2, Minimum potassium ion channel-related peptide 2, Potassium channel subunit beta MiRP2 | |
| Primary ID | Q9Y6H6 |
| Links |  -  -  |
| Type | protein |
| Relations | 3 |
| Function | Ancillary protein that assembles as a beta subunit with a voltage-gated potassium channel complex of pore-forming alpha subunits. Modulates the gating kinetics and enhances stability of the channel complex. Assembled with KCNB1 modulates the gating characteristics of the delayed rectifier voltage-dependent potassium channel KCNB1 (PubMed:12954870). Associated with KCNC4/Kv3.4 is proposed to form the subthreshold voltage-gated potassium channel in skeletal muscle and to establish the resting membrane potential (RMP) in muscle cells. Associated with KCNQ1/KCLQT1 may form the intestinal cAMP-stimulated potassium channel involved in chloride secretion that produces a current with nearly instantaneous activation with a linear current-voltage relationship. |
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Modifications Tables
Relations
| Regulator | Mechanism | target | score ℹ | |
|---|---|---|---|---|
| + | PRKCD | up-regulates activity 
phosphorylation
|
KCNE3 | 0.2 |
| Publications: | 1 | |||
| + | KCNE3 | down-regulates quantity 
relocalization
|
potassium(1+) | 0.8 |
| Publications: | 1 | Organism: | Homo Sapiens | |
| + | KCNE3 | up-regulates activity
binding
|
KCNQ1 | 0.65 |
| Publications: | 1 | |||