Summary

Name CABIN1
Full Name Calcineurin-binding protein cabin-1
Synonyms Calcineurin inhibitor, CAIN | KIAA0330
Primary ID Q9Y6J0
Links - -
Type protein
Relations 5
Function May be required for replication-independent chromatin assembly. May serve as a negative regulator of T-cell receptor (TCR) signaling via inhibition of calcineurin. Inhibition of activated calcineurin is dependent on both PKC and calcium signals. Acts as a negative regulator of p53/TP53 by keeping p53 in an inactive state on chromatin at promoters of a subset of it's target genes.

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Relations

Regulator Mechanism target score ℹ
+ CABIN1down-regulates img/indirect_inhibition.png MEF2D 0.788
Publications: 1 Organism: Homo Sapiens
+ CABIN1down-regulates img/indirect_inhibition.png MEF2A 0.666
Publications: 1 Organism: Homo Sapiens
+ CABIN1form complex img/form-complex.png binding HIRA complex 2 0.518
Publications: 1 Organism: Homo Sapiens
+ CABIN1down-regulates img/indirect_inhibition.png MEF2C 0.655
Publications: 1 Organism: Homo Sapiens
+ CABIN1form complex img/form-complex.png binding HIRA complex 1 0.684
Publications: 1 Organism: Homo Sapiens