| + |
HIRA complex 2 | up-regulates quantity by stabilization 
binding
|
H3-3A |
0.2 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-269440 |
|
|
Homo sapiens |
|
| pmid |
sentence |
| 30285846 |
H3.3 is an ancient and conserved H3 variant and plays essential roles in transcriptional regulation. HIRA complex, which is composed of HIRA, UBN1 or UBN2, and Cabin1, is a H3.3 specific chaperone complex. In this study, we demonstrate that the UBN1 or UBN2 subunit is mainly responsible for specific recognition and direct binding of H3.3 by the HIRA complex. |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
| + |
HIRA | form complex 
binding
|
HIRA complex 2 |
0.519 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-269437 |
|
|
Homo sapiens |
|
| pmid |
sentence |
| 30285846 |
H3.3 is an ancient and conserved H3 variant and plays essential roles in transcriptional regulation. HIRA complex, which is composed of HIRA, UBN1 or UBN2, and Cabin1, is a H3.3 specific chaperone complex. In this study, we demonstrate that the UBN1 or UBN2 subunit is mainly responsible for specific recognition and direct binding of H3.3 by the HIRA complex. |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
| + |
UBN2 | form complex
binding
|
HIRA complex 2 |
0.384 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-269436 |
|
|
Homo sapiens |
|
| pmid |
sentence |
| 30285846 |
H3.3 is an ancient and conserved H3 variant and plays essential roles in transcriptional regulation. HIRA complex, which is composed of HIRA, UBN1 or UBN2, and Cabin1, is a H3.3 specific chaperone complex. In this study, we demonstrate that the UBN1 or UBN2 subunit is mainly responsible for specific recognition and direct binding of H3.3 by the HIRA complex. |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
| + |
CABIN1 | form complex
binding
|
HIRA complex 2 |
0.52 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-269438 |
|
|
Homo sapiens |
|
| pmid |
sentence |
| 30285846 |
H3.3 is an ancient and conserved H3 variant and plays essential roles in transcriptional regulation. HIRA complex, which is composed of HIRA, UBN1 or UBN2, and Cabin1, is a H3.3 specific chaperone complex. In this study, we demonstrate that the UBN1 or UBN2 subunit is mainly responsible for specific recognition and direct binding of H3.3 by the HIRA complex. |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
3.0
HIRA complex 2