3.0
Summary
| Name |  SLC4A4View Modifications |
| Full Name | Electrogenic sodium bicarbonate cotransporter 1 |
| Synonyms | Sodium bicarbonate cotransporter, Na(+)/HCO3(-) cotransporter, Solute carrier family 4 member 4, kNBC1 | NBC, NBC1, NBCE1 |
| Primary ID | Q9Y6R1 |
| Links |  -  -  |
| Type | protein |
| Relations | 5 |
| Function | Electrogenic sodium/bicarbonate cotransporter with a Na(+):HCO3(-) stoichiometry varying from 1:2 to 1:3. May regulate bicarbonate influx/efflux at the basolateral membrane of cells and regulate intracellular pH. |
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Modifications Tables
Relations
| Regulator | Mechanism | target | score ℹ | |
|---|---|---|---|---|
| + | PKA | up-regulates activity 
phosphorylation
|
SLC4A4 | 0.2 |
| Publications: | 1 | Organism: | Mus Musculus | |
| + | STK39 | down-regulates activity 
phosphorylation
|
SLC4A4 | 0.356 |
| Publications: | 2 | Organism: | Mus Musculus, Homo Sapiens | |
| Tissue: | Pancreas | |||
| + | AHCYL1 | up-regulates activity
binding
|
SLC4A4 | 0.693 |
| Publications: | 1 | Organism: | Homo Sapiens | |
| + | PP1 | up-regulates activity
dephosphorylation
|
SLC4A4 | 0.2 |
| Publications: | 1 | Organism: | Mus Musculus | |
| Tissue: | Pancreas | |||