Summary

Name LY96
Full Name Lymphocyte antigen 96
Synonyms Ly-96, ESOP-1, Protein MD-2 | ESOP1, MD2
Primary ID Q9Y6Y9
Links - -
Type protein
Relations 2
Function Binds bacterial lipopolysaccharide (LPS) (PubMed:17803912, PubMed:17569869). Cooperates with TLR4 in the innate immune response to bacterial lipopolysaccharide (LPS), and with TLR2 in the response to cell wall components from Gram-positive and Gram-negative bacteria (PubMed:11160242, PubMed:11593030). Enhances TLR4-dependent activation of NF-kappa-B (PubMed:10359581). Cells expressing both LY96 and TLR4, but not TLR4 alone, respond to LPS (PubMed:10359581).

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Relations

Regulator Mechanism target score
+ up-regulates activity img/direct-activation.png binding HMGB1 0.615
Publications: 1 Organism: Mus Musculus
+ down-regulates quantity by repression img/indirect_inhibition.png transcriptional regulation LY96 0.2
Publications: 1 Organism: Homo Sapiens
Tissue: Gubernaculum Testis