| + |
NFS1 | form complex 
binding
|
Mitochondrial Fe-S Cluster Assembly Complex |
0.793 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-262127 |
|
|
in vitro |
|
| pmid |
sentence |
| 27519411 |
As the architecture of the human machinery remains undefined, we co-expressed in Escherichia coli the following four proteins involved in the initial step of Fe-S cluster synthesis: FXN42-210 (iron donor); [NFS1]·[ISD11] (sulfur donor); and ISCU (scaffold upon which new clusters are assembled). We purified a stable, active complex consisting of all four proteins with 1:1:1:1 stoichiometry. |
|
| Publications: |
1 |
Organism: |
In Vitro |
| + |
ISCU | form complex
binding
|
Mitochondrial Fe-S Cluster Assembly Complex |
0.729 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-262128 |
|
|
in vitro |
|
| pmid |
sentence |
| 27519411 |
As the architecture of the human machinery remains undefined, we co-expressed in Escherichia coli the following four proteins involved in the initial step of Fe-S cluster synthesis: FXN42-210 (iron donor); [NFS1]·[ISD11] (sulfur donor); and ISCU (scaffold upon which new clusters are assembled). We purified a stable, active complex consisting of all four proteins with 1:1:1:1 stoichiometry. |
|
| Publications: |
1 |
Organism: |
In Vitro |
| + |
LYRM4 | form complex
binding
|
Mitochondrial Fe-S Cluster Assembly Complex |
0.706 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-262126 |
|
|
in vitro |
|
| pmid |
sentence |
| 27519411 |
As the architecture of the human machinery remains undefined, we co-expressed in Escherichia coli the following four proteins involved in the initial step of Fe-S cluster synthesis: FXN42-210 (iron donor); [NFS1]·[ISD11] (sulfur donor); and ISCU (scaffold upon which new clusters are assembled). We purified a stable, active complex consisting of all four proteins with 1:1:1:1 stoichiometry. |
|
| Publications: |
1 |
Organism: |
In Vitro |
| + |
FXN | form complex
binding
|
Mitochondrial Fe-S Cluster Assembly Complex |
0.787 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-262125 |
|
|
in vitro |
|
| pmid |
sentence |
| 27519411 |
As the architecture of the human machinery remains undefined, we co-expressed in Escherichia coli the following four proteins involved in the initial step of Fe-S cluster synthesis: FXN42-210 (iron donor); [NFS1]·[ISD11] (sulfur donor); and ISCU (scaffold upon which new clusters are assembled). We purified a stable, active complex consisting of all four proteins with 1:1:1:1 stoichiometry. |
|
| Publications: |
1 |
Organism: |
In Vitro |
| + |
Mitochondrial Fe-S Cluster Assembly Complex | up-regulates quantity 
chemical modification
|
iron-sulfur cluster |
0.8 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-262129 |
|
|
in vitro |
|
| pmid |
sentence |
| 27519411 |
As the architecture of the human machinery remains undefined, we co-expressed in Escherichia coli the following four proteins involved in the initial step of Fe-S cluster synthesis: FXN42-210 (iron donor); [NFS1]·[ISD11] (sulfur donor); and ISCU (scaffold upon which new clusters are assembled). We purified a stable, active complex consisting of all four proteins with 1:1:1:1 stoichiometry. |
|
| Publications: |
1 |
Organism: |
In Vitro |
3.0
Mitochondrial Fe-S Cluster Assembly Complex
CPX-5641