| + |
Erythrocytic spectrin | down-regulates 
|
Membrane_disruption |
0.7 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-266028 |
|
|
Homo sapiens |
|
| pmid |
sentence |
| 24302288 |
Spectrin is multifunctional, and spectrin-based networks are important for maintaining the shape and mechanical properties of erythrocytes. |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
| + |
SPTB | form complex 
binding
|
Erythrocytic spectrin |
0.724 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-266024 |
|
|
Homo sapiens |
Erythrocyte |
| pmid |
sentence |
| 24302288 |
Spectrin is a large, cytoskeletal, and heterodimeric protein composed of modular structure of alpha and beta subunits, it typically contains 106 contiguous amino acid sequence motifs called “spectrin repeats”. Spectrin is crucial for maintaining the stability and structure of the cell membrane and the shape of a cell |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
| + |
Erythrocytic spectrin | up-regulates 
|
Cell_shape |
0.7 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-266032 |
|
|
Homo sapiens |
|
| pmid |
sentence |
| 24302288 |
Spectrin is multifunctional, and spectrin-based networks are important for maintaining the shape and mechanical properties of erythrocytes. |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
| + |
Erythrocytic spectrin | up-regulates 
binding
|
F-actin_assembly |
0.7 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-266030 |
|
|
Homo sapiens |
|
| pmid |
sentence |
| 24302288 |
Spectrin is a member of the F-actin-crosslinking protein superfamily. |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
| + |
SPTA1 | form complex
binding
|
Erythrocytic spectrin |
0.724 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-266025 |
|
|
Homo sapiens |
Erythrocyte |
| pmid |
sentence |
| 24302288 |
Spectrin is a large, cytoskeletal, and heterodimeric protein composed of modular structure of alpha and beta subunits, it typically contains 106 contiguous amino acid sequence motifs called “spectrin repeats”. Spectrin is crucial for maintaining the stability and structure of the cell membrane and the shape of a cell |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
3.0
Erythrocytic spectrin
CPX-2499