| + |
URI1 prefoldin co-chaperone | form complex 
binding
|
PAQosome co-chaperone complex |
0.553 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-270924 |
|
|
Homo sapiens |
|
| pmid |
sentence |
| 30484152 |
The PAQosome (Particle for Arrangement of Quaternary structure) is a large multisubunit chaperone complex that is essential for the assembly and stabilization of other macromolecular complexes. It also interacts with several chaperones including Hsp90, Hsp70, and CCT. The PAQosome is comprised of the R2TP complex, the URI1 prefoldin complex (also known as the non-canonical prefoldin-like complex), the RNA polymerase subunit RPB5, and the WD40 repeat protein WDR92. |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
| + |
PFDN2 | form complex
binding
|
URI1 prefoldin co-chaperone |
0.715 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-270919 |
|
|
Homo sapiens |
|
| pmid |
sentence |
| 30484151 |
In humans, the R2TP complex consists of orthologous proteins named RUVBL1, RUVBL2, RPAP3, and PIH1D1 and the PFDL module is composed of two α (UXT and URI1) and four β subunits (PFDN2, PFDN6, PDRG1, and one of them likely duplicated) as well as two additional members, the RNA polymerase II subunit POLR2E/RPB5, and WDR96 |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
| + |
UXT | form complex
binding
|
URI1 prefoldin co-chaperone |
0.612 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-270916 |
|
|
Homo sapiens |
|
| pmid |
sentence |
| 30484151 |
In humans, the R2TP complex consists of orthologous proteins named RUVBL1, RUVBL2, RPAP3, and PIH1D1 and the PFDL module is composed of two α (UXT and URI1) and four β subunits (PFDN2, PFDN6, PDRG1, and one of them likely duplicated) as well as two additional members, the RNA polymerase II subunit POLR2E/RPB5, and WDR93 |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
| + |
URI1 | form complex
binding
|
URI1 prefoldin co-chaperone |
0.553 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-270917 |
|
|
Homo sapiens |
|
| pmid |
sentence |
| 30484151 |
In humans, the R2TP complex consists of orthologous proteins named RUVBL1, RUVBL2, RPAP3, and PIH1D1 and the PFDL module is composed of two α (UXT and URI1) and four β subunits (PFDN2, PFDN6, PDRG1, and one of them likely duplicated) as well as two additional members, the RNA polymerase II subunit POLR2E/RPB5, and WDR94 |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
| + |
PFDN6 | form complex
binding
|
URI1 prefoldin co-chaperone |
0.623 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-270918 |
|
|
Homo sapiens |
|
| pmid |
sentence |
| 30484151 |
In humans, the R2TP complex consists of orthologous proteins named RUVBL1, RUVBL2, RPAP3, and PIH1D1 and the PFDL module is composed of two α (UXT and URI1) and four β subunits (PFDN2, PFDN6, PDRG1, and one of them likely duplicated) as well as two additional members, the RNA polymerase II subunit POLR2E/RPB5, and WDR95 |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
| + |
PDRG1 | form complex
binding
|
URI1 prefoldin co-chaperone |
0.569 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-270915 |
|
|
Homo sapiens |
|
| pmid |
sentence |
| 30484151 |
In humans, the R2TP complex consists of orthologous proteins named RUVBL1, RUVBL2, RPAP3, and PIH1D1 and the PFDL module is composed of two α (UXT and URI1) and four β subunits (PFDN2, PFDN6, PDRG1, and one of them likely duplicated) as well as two additional members, the RNA polymerase II subunit POLR2E/RPB5, and WDR92 |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
3.0
URI1 prefoldin co-chaperone
CPX-6144