| + |
POLR2E | form complex 
binding
|
PAQosome co-chaperone complex |
0.2 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-270923 |
|
|
Homo sapiens |
|
| pmid |
sentence |
| 30484152 |
The PAQosome (Particle for Arrangement of Quaternary structure) is a large multisubunit chaperone complex that is essential for the assembly and stabilization of other macromolecular complexes. It also interacts with several chaperones including Hsp90, Hsp70, and CCT. The PAQosome is comprised of the R2TP complex, the URI1 prefoldin complex (also known as the non-canonical prefoldin-like complex), the RNA polymerase subunit RPB5, and the WD40 repeat protein WDR92. |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
| + |
PAQosome co-chaperone complex | up-regulates 
|
Chaperone-mediated protein folding |
0.7 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-270920 |
|
|
Homo sapiens |
|
| pmid |
sentence |
| 29203338 |
The PAQosome, an R2TP-Based Chaperone for Quaternary Structure Formation. The Rvb1-Rvb2-Tah1-Pih1/prefoldin-like (R2TP/PFDL) complex is a unique chaperone that provides a platform for the assembly and maturation of many key multiprotein complexes in mammalian cells. Here, we propose to rename R2TP/PFDL as PAQosome (particle for arrangement of quaternary structure) to more accurately represent its unique function. |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
| + |
URI1 prefoldin co-chaperone | form complex
binding
|
PAQosome co-chaperone complex |
0.589 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-270924 |
|
|
Homo sapiens |
|
| pmid |
sentence |
| 30484152 |
The PAQosome (Particle for Arrangement of Quaternary structure) is a large multisubunit chaperone complex that is essential for the assembly and stabilization of other macromolecular complexes. It also interacts with several chaperones including Hsp90, Hsp70, and CCT. The PAQosome is comprised of the R2TP complex, the URI1 prefoldin complex (also known as the non-canonical prefoldin-like complex), the RNA polymerase subunit RPB5, and the WD40 repeat protein WDR92. |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
| + |
R2TP core co-chaperone | form complex
binding
|
PAQosome co-chaperone complex |
0.61 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-270925 |
|
|
Homo sapiens |
|
| pmid |
sentence |
| 30484152 |
The PAQosome (Particle for Arrangement of Quaternary structure) is a large multisubunit chaperone complex that is essential for the assembly and stabilization of other macromolecular complexes. It also interacts with several chaperones including Hsp90, Hsp70, and CCT. The PAQosome is comprised of the R2TP complex, the URI1 prefoldin complex (also known as the non-canonical prefoldin-like complex), the RNA polymerase subunit RPB5, and the WD40 repeat protein WDR92. |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
| + |
ASDURF | form complex
binding
|
PAQosome co-chaperone complex |
0.2 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-270922 |
|
|
Homo sapiens |
|
| pmid |
sentence |
| 30484152 |
The PAQosome (Particle for Arrangement of Quaternary structure) is a large multisubunit chaperone complex that is essential for the assembly and stabilization of other macromolecular complexes. It also interacts with several chaperones including Hsp90, Hsp70, and CCT. The PAQosome is comprised of the R2TP complex, the URI1 prefoldin complex (also known as the non-canonical prefoldin-like complex), the RNA polymerase subunit RPB5, and the WD40 repeat protein WDR92. |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
| + |
DNAAF10 | form complex
binding
|
PAQosome co-chaperone complex |
0.2 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-270921 |
|
|
Homo sapiens |
|
| pmid |
sentence |
| 30484152 |
The PAQosome (Particle for Arrangement of Quaternary structure) is a large multisubunit chaperone complex that is essential for the assembly and stabilization of other macromolecular complexes. It also interacts with several chaperones including Hsp90, Hsp70, and CCT. The PAQosome is comprised of the R2TP complex, the URI1 prefoldin complex (also known as the non-canonical prefoldin-like complex), the RNA polymerase subunit RPB5, and the WD40 repeat protein WDR92. |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
3.0
PAQosome co-chaperone complex
CPX-6145