| + |
STX17-VAMP8 SNARE complex | up-regulates activity 
|
Membrane_fusion |
0.7 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-273712 |
|
|
Homo sapiens |
HEK-293 Cell |
| pmid |
sentence |
| 23217709 |
Here, we identify syntaxin 17 (Stx17) as the autophagosomal SNARE required for fusion with the endosome/lysosome. Stx17 localizes to the outer membrane of completed autophagosomes but not to the isolation membrane (unclosed intermediate structures); for this reason, the lysosome does not fuse with the isolation membrane. Stx17 interacts with SNAP-29 and the endosomal/lysosomal SNARE VAMP8. |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
| + |
VAMP8 | form complex 
binding
|
STX17-VAMP8 SNARE complex |
0.918 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-273711 |
|
|
Homo sapiens |
HEK-293 Cell |
| pmid |
sentence |
| 23217709 |
Here, we identify syntaxin 17 (Stx17) as the autophagosomal SNARE required for fusion with the endosome/lysosome. Stx17 localizes to the outer membrane of completed autophagosomes but not to the isolation membrane (unclosed intermediate structures); for this reason, the lysosome does not fuse with the isolation membrane. Stx17 interacts with SNAP-29 and the endosomal/lysosomal SNARE VAMP8. |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
| + |
SNAP29 | form complex
binding
|
STX17-VAMP8 SNARE complex |
0.941 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-273710 |
|
|
Homo sapiens |
HEK-293 Cell |
| pmid |
sentence |
| 23217709 |
Here, we identify syntaxin 17 (Stx17) as the autophagosomal SNARE required for fusion with the endosome/lysosome. Stx17 localizes to the outer membrane of completed autophagosomes but not to the isolation membrane (unclosed intermediate structures); for this reason, the lysosome does not fuse with the isolation membrane. Stx17 interacts with SNAP-29 and the endosomal/lysosomal SNARE VAMP8. |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
| + |
STX17 | form complex
binding
|
STX17-VAMP8 SNARE complex |
0.921 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-273709 |
|
|
Homo sapiens |
HEK-293 Cell |
| pmid |
sentence |
| 23217709 |
Here, we identify syntaxin 17 (Stx17) as the autophagosomal SNARE required for fusion with the endosome/lysosome. Stx17 localizes to the outer membrane of completed autophagosomes but not to the isolation membrane (unclosed intermediate structures); for this reason, the lysosome does not fuse with the isolation membrane. Stx17 interacts with SNAP-29 and the endosomal/lysosomal SNARE VAMP8. |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
3.0
STX17-VAMP8 SNARE complex