| + |
SZT2 | form complex 
binding
|
KICSTOR complex |
0.751 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-280996 |
|
|
Homo sapiens |
|
| pmid |
sentence |
| 28199306 |
Here we identify a protein complex (KICSTOR) that is composed of four proteins, KPTN, ITFG2, C12orf66 and SZT2, and that is required for amino acid or glucose deprivation to inhibit mTORC1 in cultured human cells. |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
| + |
ITFG2 | form complex
binding
|
KICSTOR complex |
0.847 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-280997 |
|
|
Homo sapiens |
|
| pmid |
sentence |
| 28199306 |
Here we identify a protein complex (KICSTOR) that is composed of four proteins, KPTN, ITFG2, C12orf66 and SZT2, and that is required for amino acid or glucose deprivation to inhibit mTORC1 in cultured human cells. |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
| + |
C12orf66 | form complex
binding
|
KICSTOR complex |
0.778 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-280998 |
|
|
Homo sapiens |
|
| pmid |
sentence |
| 28199306 |
Here we identify a protein complex (KICSTOR) that is composed of four proteins, KPTN, ITFG2, C12orf66 and SZT2, and that is required for amino acid or glucose deprivation to inhibit mTORC1 in cultured human cells. |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
| + |
KPTN | form complex
binding
|
KICSTOR complex |
0.812 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-280999 |
|
|
Homo sapiens |
|
| pmid |
sentence |
| 28199306 |
Here we identify a protein complex (KICSTOR) that is composed of four proteins, KPTN, ITFG2, C12orf66 and SZT2, and that is required for amino acid or glucose deprivation to inhibit mTORC1 in cultured human cells. |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
| + |
KICSTOR complex | up-regulates activity 
binding
|
GATOR1 |
0.487 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-281000 |
|
|
Homo sapiens |
|
| pmid |
sentence |
| 28199306 |
KICSTOR localizes to lysosomes; binds and recruits GATOR1, but not GATOR2, to the lysosomal surface; and is necessary for the interaction of GATOR1 with its substrates, the Rag GTPases, and with GATOR2. |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
4.0
KICSTOR complex