| + |
IBA57 | form complex 
binding
|
ISCA2-IBA57 mitochondrial iron-sulfur protein assembly complex |
0.568 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-281058 |
|
|
|
|
| pmid |
sentence |
| 31831856 |
In mitochondria, a complex protein machinery is devoted to the maturation of iron-sulfur cluster proteins. Structural information on the last steps of the machinery, which involve ISCA1, ISCA2 and IBA57 proteins, needs to be acquired in order to define how these proteins cooperate each other. We report here the use of an integrative approach, utilizing information from small-angle X-ray scattering (SAXS) and bioinformatics-driven docking prediction, to determine a low-resolution structural model of the human mitochondrial [2Fe-2S]2+ ISCA2-IBA57 complex. |
|
| Publications: |
1 |
| + |
ISCA2 | form complex
binding
|
ISCA2-IBA57 mitochondrial iron-sulfur protein assembly complex |
0.568 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-281059 |
|
|
|
|
| pmid |
sentence |
| 31831856 |
In mitochondria, a complex protein machinery is devoted to the maturation of iron-sulfur cluster proteins. Structural information on the last steps of the machinery, which involve ISCA1, ISCA2 and IBA57 proteins, needs to be acquired in order to define how these proteins cooperate each other. We report here the use of an integrative approach, utilizing information from small-angle X-ray scattering (SAXS) and bioinformatics-driven docking prediction, to determine a low-resolution structural model of the human mitochondrial [2Fe-2S]2+ ISCA2-IBA57 complex. |
|
| Publications: |
1 |
| + |
ISCA2-IBA57 mitochondrial iron-sulfur protein assembly complex | up-regulates quantity 
chemical modification
|
iron-sulfur cluster |
0.8 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-281060 |
|
|
|
|
| pmid |
sentence |
| 31831856 |
In mitochondria, a complex protein machinery is devoted to the maturation of iron-sulfur cluster proteins. Structural information on the last steps of the machinery, which involve ISCA1, ISCA2 and IBA57 proteins, needs to be acquired in order to define how these proteins cooperate each other. We report here the use of an integrative approach, utilizing information from small-angle X-ray scattering (SAXS) and bioinformatics-driven docking prediction, to determine a low-resolution structural model of the human mitochondrial [2Fe-2S]2+ ISCA2-IBA57 complex. |
|
| Publications: |
1 |
4.0
ISCA2-IBA57 mitochondrial iron-sulfur protein assembly complex