| + |
PSMG1 | form complex 
binding
|
PAC1-PAC2 proteasomal chaperone complex |
0.647 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-281315 |
|
|
Homo sapiens |
|
| pmid |
sentence |
| 18786393 |
The 26S proteasome mediates ubiquitin-dependent proteolysis in eukaryotic cells. A number of studies including very recent ones have revealed that assembly of its 20S catalytic core particle is an ordered process that involves several conserved proteasome assembly chaperones (PACs). Two heterodimeric chaperones, PAC1-PAC2 and PAC3-PAC4, promote the assembly of rings composed of seven alpha subunits. Subsequently, beta subunits join to form half-proteasome precursor complexes containing all but one of the 14 subunits. |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
| + |
PSMG2 | form complex
binding
|
PAC1-PAC2 proteasomal chaperone complex |
0.647 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-281316 |
|
|
Homo sapiens |
|
| pmid |
sentence |
| 18786393 |
The 26S proteasome mediates ubiquitin-dependent proteolysis in eukaryotic cells. A number of studies including very recent ones have revealed that assembly of its 20S catalytic core particle is an ordered process that involves several conserved proteasome assembly chaperones (PACs). Two heterodimeric chaperones, PAC1-PAC2 and PAC3-PAC4, promote the assembly of rings composed of seven alpha subunits. Subsequently, beta subunits join to form half-proteasome precursor complexes containing all but one of the 14 subunits. |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
| + |
PAC1-PAC2 proteasomal chaperone complex | up-regulates quantity by stabilization 
binding
|
26S Proteasome |
0.379 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-281319 |
|
|
Homo sapiens |
|
| pmid |
sentence |
| 18786393 |
The 26S proteasome mediates ubiquitin-dependent proteolysis in eukaryotic cells. A number of studies including very recent ones have revealed that assembly of its 20S catalytic core particle is an ordered process that involves several conserved proteasome assembly chaperones (PACs). Two heterodimeric chaperones, PAC1-PAC2 and PAC3-PAC4, promote the assembly of rings composed of seven alpha subunits. Subsequently, beta subunits join to form half-proteasome precursor complexes containing all but one of the 14 subunits. |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
4.0
PAC1-PAC2 proteasomal chaperone complex