| + |
CLTRN | form complex
binding
|
B(0)AT3-Collectrin heteromeric amino acid transporter complex |
0.2 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-281349 |
|
|
Mus musculus |
|
| pmid |
sentence |
| 26240152 |
The main apical membrane neutral amino acid transporters in mouse intestine and kidney, B0AT1 and B0AT3, require the ancillary protein collectrin or ACE2 for plasma membrane expression. |
|
| Publications: |
1 |
Organism: |
Mus Musculus |
| + |
SLC6A18 | form complex
binding
|
B(0)AT3-Collectrin heteromeric amino acid transporter complex |
0.2 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-281348 |
|
|
Mus musculus |
|
| pmid |
sentence |
| 26240152 |
The main apical membrane neutral amino acid transporters in mouse intestine and kidney, B0AT1 and B0AT3, require the ancillary protein collectrin or ACE2 for plasma membrane expression. Utilizing monocarboxylate-B(0)AT1/3 fusion constructs, we discovered that collectrin is also necessary for B(0)AT1 and B(0)AT3 catalytic function. |
|
| Publications: |
1 |
Organism: |
Mus Musculus |
| + |
STX3 | down-regulates activity
binding
|
B(0)AT3-Collectrin heteromeric amino acid transporter complex |
0.273 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-281351 |
|
|
Mus musculus |
|
| pmid |
sentence |
| 26240152 |
Utilizing monocarboxylate-B(0)AT1/3 fusion constructs, we discovered that collectrin is also necessary for B(0)AT1 and B(0)AT3 catalytic function. Syntaxin 1A and syntaxin 3 inhibit the membrane expression of B(0)AT1 by competing with collectrin for access. |
|
| Publications: |
1 |
Organism: |
Mus Musculus |