| + |
CAMK2A | down-regulates activity 
phosphorylation
|
HOMER |
0.396 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-264699 |
|
|
in vitro |
|
| pmid |
sentence |
| 18480293 |
Homer3 is phosphorylated at Ser120, Ser159, and Ser176 by CaMKII in vitro. Homer3 phosphorylation reduces its affinity for target molecules and modulates the Ca2+ signaling patterns induced by mGluR1α activation |
|
| Publications: |
1 |
Organism: |
In Vitro |
| Pathways: | Glutamatergic synapse |
| + |
HOMER | up-regulates activity 
binding
|
SHANK1 |
0.2 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-264698 |
|
|
Homo sapiens |
|
| pmid |
sentence |
| 17243894 |
It has been shown that Homer, a scaffold protein with a single EVH1 domain that binds to Shank, mGluR1, and other postsynaptic proteins (98) (Figure 3), exists as a tetramer, thus allowing it to cross-link several interacting proteins in the PSD |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
| Pathways: | Glutamatergic synapse |
| + |
HOMER | up-regulates activity
binding
|
SHANK3 |
0.2 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-264697 |
|
|
Homo sapiens |
Neuron |
| pmid |
sentence |
| 17243894 |
It has been shown that Homer, a scaffold protein with a single EVH1 domain that binds to Shank, mGluR1, and other postsynaptic proteins (98) (Figure 3), exists as a tetramer, thus allowing it to cross-link several interacting proteins in the PSD |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
| Pathways: | Glutamatergic synapse |
4.0
HOMER