| + |
MAPK12 | up-regulates quantity by expression 
transcriptional regulation
|
Satellite_cells_self-renewal |
0.7 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-255902 |
|
|
Mus musculus |
Satellite Cell |
| pmid |
sentence |
| 29681515 |
[...] we observed a significant diminution in the number of symmetric satellite stem cell (YFP–) divisions in p38 gamma siRNA-treated fibers, suggesting that p38 gamma is required for symmetric stem cell maintenance. Thus, loss of p38gamma greatly skewed the ratio of asymmetric to symmetric satellite stem cell divisions to favor asymmetric divisions and myogenic commitment at the expense of self-renewal |
|
| Publications: |
1 |
Organism: |
Mus Musculus |
| Tissue: |
Skeletal Muscle |
| + |
ROCK1 | up-regulates
transcriptional regulation
|
Satellite_cells_self-renewal |
0.7 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-255850 |
|
|
|
|
| pmid |
sentence |
| 23290138 |
FN in the satellite cell niche is required for the maintenance of the overall satellite cell pool during muscle regeneration. Moreover, FN is necessary to potentiate Wnt7a signaling through the Fzd7/Scd4 receptor complex, which controls the regulation of satellite stem cell numbers |
|
| Publications: |
1 |
| Tissue: |
Skeletal Muscle |
3.0
Satellite_cells_self-renewal