| + |
TOM40 complex | up-regulates 
|
Insertion into mitochondrial membrane |
0.7 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-267688 |
|
|
|
|
| pmid |
sentence |
| 18423394 |
The sorting and assembly pathway of outer membrane proteins involves three machineries: the translocase of the outer membrane (TOM complex) the sorting and assembly machinery (SAM complex) and the MDM complex (mitochondrial distribution and morphology). |
|
| Publications: |
1 |
| + |
SAM complex | up-regulates
|
Insertion into mitochondrial membrane |
0.7 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-267687 |
|
|
|
|
| pmid |
sentence |
| 33408415 |
The mitochondrial outer membrane contains so-called β-barrel proteins, which allow communication between the cytosol and the mitochondrial interior1-3. Insertion of β-barrel proteins into the outer membrane is mediated by the multisubunit mitochondrial sorting and assembly machinery (SAM, also known as TOB) |
|
| Publications: |
1 |
| + |
TIM23 complex | up-regulates
|
Insertion into mitochondrial membrane |
0.7 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-267709 |
|
|
|
|
| pmid |
sentence |
| 32074073 |
Mitochondrial precursor proteins with amino-terminal presequences are imported via the presequence pathway, utilizing the TIM23 complex for inner membrane translocation. Initially, the precursors pass the outer membrane through the TOM complex and are handed over to the TIM23 complex where they are sorted into the inner membrane or translocated into the matrix. |
|
| Publications: |
1 |
| + |
TIM22 complex | up-regulates
|
Insertion into mitochondrial membrane |
0.7 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-267710 |
|
|
|
|
| pmid |
sentence |
| 32901109 |
The TIM22 complex is responsible for the translocation and insertion of hydrophobic membrane proteins, including mitochondrial carrier proteins and translocase subunits (Tim17, Tim22 and Tim23) |
|
| Publications: |
1 |
3.0
Insertion into mitochondrial membrane