4.0
Summary
| Name |  Cytosolic DNA
|
| Primary ID | SIGNOR-ST30 |
| Type | stimulus |
| Description | Cytosolic DNA derived from either pathogens (non-self-DNA, including viral and bacterial DNA) or host genome (self-DNA, including damaged mitochondrial DNA (mtDNA), leaked/damaged nuclear DNA from chromosome instability (CIN), cytosolic DNA in micronuclei and from cell debris), are powerful activators for the innate-immune system. PMID: 33927185 |
| Relations | 1 |
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Relations
| Regulator | Mechanism | target | score ℹ | |
|---|---|---|---|---|
| + | Cytosolic DNA | up-regulates 
|
POLR3A | 0.7 |
| Publications: | 1 | Organism: | Homo Sapiens | |