Glycogenesis
Pathway ID: SIGNOR-G
Description: Glycogenesis is the process of glycogen synthesis. Glycogen is a polymer of glucose residues that is linked by α-1,4 and α-1,6 glycosidic bonds. Glycogenin initiates the process by self glycosylation of a short 8–12 glucose oligosaccharide primer. Glycogen synthase (GYS) utilises UDP-glucose as the glucosyl donor and elongates the glucose oligossacharide primer. Glycogen branching enzyme 1 (GBE1) generates α-1,6-glucosidic branches from α-1,4-linked glucose chains, to increase solubility of the glycogen polymer.
Curated by: Marta Iannuccelli
Description: Glycogenesis is the process of glycogen synthesis. Glycogen is a polymer of glucose residues that is linked by α-1,4 and α-1,6 glycosidic bonds. Glycogenin initiates the process by self glycosylation of a short 8–12 glucose oligosaccharide primer. Glycogen synthase (GYS) utilises UDP-glucose as the glucosyl donor and elongates the glucose oligossacharide primer. Glycogen branching enzyme 1 (GBE1) generates α-1,6-glucosidic branches from α-1,4-linked glucose chains, to increase solubility of the glycogen polymer.
Curated by: Marta Iannuccelli
17 Seed Entities
Organism:
|
Name | Primary ID |
|---|---|
| alpha-D-glucose 1-phosphate(2-) | CHEBI:58601 |
| glycogen | CHEBI:28087 |
| Gluconeogenesis | SIGNOR-PH35 |
| α-D-glucose | CHEBI:17925 |
| Hexokinase | SIGNOR-PF76 |
| α-D-glucosyl-glycogenin | SIGNOR-C430 |
| PYG | SIGNOR-PF96 |
| UGP2 | Q16851 |
| UTP(4-) | CHEBI:46398 |
| Glycogenin | SIGNOR-PF95 |
| alpha-D-glucose 6-phosphate(2-) | CHEBI:58225 |
| GBE1 | Q04446 |
| PGM2 | Q96G03 |
| GYS1 | P13807 |
| UDP-alpha-D-glucose(2-) | CHEBI:58885 |
| GYS2 | P54840 |
| PGM1 | P36871 |
4.0