Glycogenesis

Pathway ID: SIGNOR-G

Description: Glycogenesis is the process of glycogen synthesis. Glycogen is a polymer of glucose residues that is linked by α-1,4 and α-1,6 glycosidic bonds. Glycogenin initiates the process by self glycosylation of a short 8–12 glucose oligosaccharide primer. Glycogen synthase (GYS) utilises UDP-glucose as the glucosyl donor and elongates the glucose oligossacharide primer. Glycogen branching enzyme 1 (GBE1) generates α-1,6-glucosidic branches from α-1,4-linked glucose chains, to increase solubility of the glycogen polymer.

Curated by: Marta Iannuccelli

17 Seed Entities

Organism:
Name Primary ID
alpha-D-glucose 1-phosphate(2-) CHEBI:58601
glycogen CHEBI:28087
Gluconeogenesis SIGNOR-PH35
α-D-glucose CHEBI:17925
Hexokinase SIGNOR-PF76
α-D-glucosyl-glycogenin SIGNOR-C430
PYG SIGNOR-PF96
UGP2 Q16851
UTP(4-) CHEBI:46398
Glycogenin SIGNOR-PF95
alpha-D-glucose 6-phosphate(2-) CHEBI:58225
GBE1 Q04446
PGM2 Q96G03
GYS1 P13807
UDP-alpha-D-glucose(2-) CHEBI:58885
GYS2 P54840
PGM1 P36871