| + |
PYG | down-regulates quantity 
chemical modification
|
glycogen |
0.8 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-267953 |
|
|
Homo sapiens |
|
| pmid |
sentence |
| 3346228 |
Mammalian glycogen phosphorylases are found in at least three isozymic forms that can be distinguished by functional and structural properties as well as by the tissues in which they are preferentially expressed […] Each phosphorylase isozyme fulfills different physiological requirements even though all forms of the enzyme catalyze the same reaction, the phosphorolysis of glycogen to yield glucose 1-phosphate. |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
| Pathways: | Glycogenesis, Glycogenolysis |
| + |
PYGM | down-regulates quantity
chemical modification
|
glycogen |
0.8 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-267389 |
|
|
Homo sapiens |
|
| pmid |
sentence |
| 3346228 |
Mammalian glycogen phosphorylases are found in at least three isozymic forms that can be distinguished by functional and structural properties as well as by the tissues in which they are preferentially expressed […] Each phosphorylase isozyme fulfills different physiological requirements even though all forms of the enzyme catalyze the same reaction, the phosphorolysis of glycogen to yield glucose 1-phosphate. |
|
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-267948 |
|
|
Homo sapiens |
|
| pmid |
sentence |
| 3346228 |
Mammalian glycogen phosphorylases are found in at least three isozymic forms that can be distinguished by functional and structural properties as well as by the tissues in which they are preferentially expressed […] Each phosphorylase isozyme fulfills different physiological requirements even though all forms of the enzyme catalyze the same reaction, the phosphorolysis of glycogen to yield glucose 1-phosphate. |
|
| Publications: |
2 |
Organism: |
Homo Sapiens |
| + |
glycogen | up-regulates activity 
chemical activation
|
PYGB |
0.8 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-267951 |
|
|
Homo sapiens |
|
| pmid |
sentence |
| 3346228 |
Mammalian glycogen phosphorylases are found in at least three isozymic forms that can be distinguished by functional and structural properties as well as by the tissues in which they are preferentially expressed […] Each phosphorylase isozyme fulfills different physiological requirements even though all forms of the enzyme catalyze the same reaction, the phosphorolysis of glycogen to yield glucose 1-phosphate. |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
| + |
glycogen | up-regulates quantity
precursor of
|
alpha-D-glucose 1-phosphate(2-) |
0.8 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-267391 |
|
|
Homo sapiens |
|
| pmid |
sentence |
| 3346228 |
Mammalian glycogen phosphorylases are found in at least three isozymic forms that can be distinguished by functional and structural properties as well as by the tissues in which they are preferentially expressed […] Each phosphorylase isozyme fulfills different physiological requirements even though all forms of the enzyme catalyze the same reaction, the phosphorolysis of glycogen to yield glucose 1-phosphate. |
|
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-267955 |
|
|
Homo sapiens |
|
| pmid |
sentence |
| 3346228 |
Mammalian glycogen phosphorylases are found in at least three isozymic forms that can be distinguished by functional and structural properties as well as by the tissues in which they are preferentially expressed […] Each phosphorylase isozyme fulfills different physiological requirements even though all forms of the enzyme catalyze the same reaction, the phosphorolysis of glycogen to yield glucose 1-phosphate. |
|
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-267950 |
|
|
Homo sapiens |
|
| pmid |
sentence |
| 3346228 |
Mammalian glycogen phosphorylases are found in at least three isozymic forms that can be distinguished by functional and structural properties as well as by the tissues in which they are preferentially expressed […] Each phosphorylase isozyme fulfills different physiological requirements even though all forms of the enzyme catalyze the same reaction, the phosphorolysis of glycogen to yield glucose 1-phosphate. |
|
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-267394 |
|
|
Homo sapiens |
|
| pmid |
sentence |
| 3346228 |
Mammalian glycogen phosphorylases are found in at least three isozymic forms that can be distinguished by functional and structural properties as well as by the tissues in which they are preferentially expressed […] Each phosphorylase isozyme fulfills different physiological requirements even though all forms of the enzyme catalyze the same reaction, the phosphorolysis of glycogen to yield glucose 1-phosphate. |
|
| Publications: |
4 |
Organism: |
Homo Sapiens |
| Pathways: | Glycogenesis, Glycogenolysis |
| + |
glycogen | up-regulates quantity
precursor of
|
α-D-glucose |
0.8 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-267397 |
|
|
Homo sapiens |
|
| pmid |
sentence |
| 3346228 |
Mammalian glycogen phosphorylases are found in at least three isozymic forms that can be distinguished by functional and structural properties as well as by the tissues in which they are preferentially expressed […] Each phosphorylase isozyme fulfills different physiological requirements even though all forms of the enzyme catalyze the same reaction, the phosphorolysis of glycogen to yield glucose 1-phosphate. |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
| Pathways: | Glycogenesis, Glycogenolysis |
| + |
PYGL | down-regulates quantity
chemical modification
|
glycogen |
0.8 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-267392 |
|
|
Homo sapiens |
|
| pmid |
sentence |
| 3346228 |
Mammalian glycogen phosphorylases are found in at least three isozymic forms that can be distinguished by functional and structural properties as well as by the tissues in which they are preferentially expressed […] Each phosphorylase isozyme fulfills different physiological requirements even though all forms of the enzyme catalyze the same reaction, the phosphorolysis of glycogen to yield glucose 1-phosphate. |
|
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-267949 |
|
|
Homo sapiens |
|
| pmid |
sentence |
| 3346228 |
Mammalian glycogen phosphorylases are found in at least three isozymic forms that can be distinguished by functional and structural properties as well as by the tissues in which they are preferentially expressed […] Each phosphorylase isozyme fulfills different physiological requirements even though all forms of the enzyme catalyze the same reaction, the phosphorolysis of glycogen to yield glucose 1-phosphate. |
|
| Publications: |
2 |
Organism: |
Homo Sapiens |
| + |
PYGB | down-regulates quantity
chemical modification
|
glycogen |
0.8 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-267395 |
|
|
Homo sapiens |
|
| pmid |
sentence |
| 3346228 |
Mammalian glycogen phosphorylases are found in at least three isozymic forms that can be distinguished by functional and structural properties as well as by the tissues in which they are preferentially expressed […] Each phosphorylase isozyme fulfills different physiological requirements even though all forms of the enzyme catalyze the same reaction, the phosphorolysis of glycogen to yield glucose 1-phosphate. |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
| + |
α-D-glucosyl-glycogenin | up-regulates quantity
precursor of
|
glycogen |
0.8 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-268138 |
|
|
Homo sapiens |
|
| pmid |
sentence |
| 26199317 |
Glycogen branching enzyme 1 (GBE1) plays an essential role in glycogen biosynthesis by generating α-1,6-glucosidic branches from α-1,4-linked glucose chains, to increase solubility of the glycogen polymer. In eukaryotes, glycogenin (EC 2.4.1.186) initiates the synthesis of the linear glucan chain (2), which is elongated by glycogen synthase (GYS, EC 2.4.1.11) (3), functioning in concert with glycogen branching enzyme (GBE, EC 2.4.1.18) to introduce side chains |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
| Pathways: | Glycogenesis |
| + |
GBE1 | up-regulates quantity
chemical modification
|
glycogen |
0.8 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-267942 |
|
|
Homo sapiens |
|
| pmid |
sentence |
| 26199317 |
Glycogen branching enzyme 1 (GBE1) plays an essential role in glycogen biosynthesis by generating α-1,6-glucosidic branches from α-1,4-linked glucose chains, to increase solubility of the glycogen polymer. In eukaryotes, glycogenin (EC 2.4.1.186) initiates the synthesis of the linear glucan chain (2), which is elongated by glycogen synthase (GYS, EC 2.4.1.11) (3), functioning in concert with glycogen branching enzyme (GBE, EC 2.4.1.18) to introduce side chains |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
| Pathways: | Glycogenesis |
3.0
glycogen