| + |
vitamin D | up-regulates quantity 
precursor of
|
calcidiol |
0.8 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-270567 |
|
|
Homo sapiens |
|
| pmid |
sentence |
| 30080183 |
Vitamin D-binding protein transports vitamin D to the liver, where it undergoes 25-hydroxylation by CYP2R1. CYP27B1 further hydroxylates 25-hydroxyvitamin D at the 1-alpha position, resulting in the formation of the active hormone 1,25-dihydroxyvitamin D. |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
| Tissue: |
Liver |
| Pathways: | Vitamin-D Metabolism |
| + |
GC | up-regulates quantity
relocalization
|
vitamin D |
0.8 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-270566 |
|
|
Homo sapiens |
|
| pmid |
sentence |
| 30080183 |
Vitamin D-binding protein transports vitamin D to the liver, where it undergoes 25-hydroxylation by CYP2R1. CYP27B1 further hydroxylates 25-hydroxyvitamin D at the 1-alpha position, resulting in the formation of the active hormone 1,25-dihydroxyvitamin D. |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
| Tissue: |
Liver |
| Pathways: | Vitamin-D Metabolism |
| + |
CYP2R1 | down-regulates quantity 
chemical modification
|
vitamin D |
0.8 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-270569 |
|
|
Homo sapiens |
|
| pmid |
sentence |
| 30080183 |
Vitamin D-binding protein transports vitamin D to the liver, where it undergoes 25-hydroxylation by CYP2R1. CYP27B1 further hydroxylates 25-hydroxyvitamin D at the 1-alpha position, resulting in the formation of the active hormone 1,25-dihydroxyvitamin D. |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
| Tissue: |
Liver |
| Pathways: | Vitamin-D Metabolism |
| + |
calciol | up-regulates quantity
precursor of
|
vitamin D |
0.8 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-270564 |
|
|
Homo sapiens |
|
| pmid |
sentence |
| 30080183 |
Ultraviolet radiation results in the conversion of 7-dehydrocholesterol to pre-vitamin D, which isomerizes to vitamin D in the skin |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
| Tissue: |
Skin |
| Pathways: | Vitamin-D Metabolism |
| + |
Food intake | up-regulates quantity 
|
vitamin D |
0.7 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-270565 |
|
|
Homo sapiens |
|
| pmid |
sentence |
| 30080183 |
Ultraviolet radiation results in the conversion of 7-dehydrocholesterol to pre-vitamin D, which isomerizes to vitamin D in the skin. Vitamin D can also be obtained from nutrition. |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
| Pathways: | Vitamin-D Metabolism |
3.0
vitamin D