3.0
Summary
| Name |  vandetanib
|
| Synonyms | 4-BROMO-2-FLUORO-N-[(4E)-6-METHOXY-7-[(1-METHYLPIPERIDIN-4-YL)METHOXY]QUINAZOLIN-4(1H)-YLIDENE]ANILINE (PDBeChem), vandetanib (KEGG DRUG), Zactima (ChemIDplus), ZD 6474 (ChemIDplus), ZD6474 (ChemIDplus) |
| IUPAC | N-(4-bromo-2-fluorophenyl)-6-methoxy-7-[(1-methylpiperidin-4-yl)methoxy]quinazolin-4-amine |
| Formula | C22H24BrFN4O2 |
| PRIMARY ID (Read more) |
CHEBI:49960 |
| Type | chemical |
| Relations | 4 |
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Relations
| Regulator | Mechanism | target | score ℹ | |
|---|---|---|---|---|
| + | vandetanib | down-regulates activity 
chemical inhibition
|
EGFR | 0.8 |
| Publications: | 1 | Organism: | In Vitro | |
| + | vandetanib | down-regulates activity
chemical inhibition
|
KDR | 0.8 |
| Publications: | 1 | Organism: | In Vitro | |
| + | vandetanib | down-regulates
chemical inhibition
|
KDR | 0.8 |
| Publications: | 1 | Organism: | Homo Sapiens | |
| + | vandetanib | down-regulates activity
chemical inhibition
|
RET | 0.8 |
| Publications: | 1 | Organism: | In Vitro | |