3.0
Summary
| Name |  everolimus
|
| Synonyms | (1R,9S,12S,15R,16E,18R,19R,21R,23S,24E,26E,28E,30S,35R)-1,18-dihydroxy-12-{(2R)-1-[(1S,3R,4R)-4-(2-hydroxyethoxy)-3-methoxycyclohexyl]propan-2-yl}-19,30-dimethoxy-15,17,21,23,29,35-hexamethyl-11,36-dioxa-4-azatricyclo[30.3.1.0(4,9)]hexatriaconta-16,24,26,28-tetraene-2,3,10,14,20-pentone (IUPAC), 40-O-(2-hydroxyethyl)-rapamycin (ChemIDplus), 42-O-(2-Hydroxyethyl)rapamycin (ChemIDplus), Afinitor (ChemIDplus), Everolimus (ChemIDplus), everolimus (WHO MedNet), everolimus (WHO MedNet), everolimus (WHO MedNet), everolimusum (WHO MedNet) |
| IUPAC | (3S,6R,7E,9R,10R,12R,14S,15E,17E,19E,21S,23S,26R,27R,34aS)-9,27-dihydroxy-3-{(2R)-1-[(1S,3R,4R)-4-(2-hydroxyethoxy)-3-methoxycyclohexyl]propan-2-yl}-10,21-dimethoxy-6,8,12,14,20,26-hexamethyl-9,10,12,13,14,21,22,23,24,25,26,27,32,33,34,34a-hexadecahydro-3H-23,27-epoxypyrido[2,1-c][1,4]oxazacyclohentriacontine-1,5,11,28,29(4H,6H,31H)-pentone |
| Formula | C53H83NO14 |
| PRIMARY ID (Read more) |
CHEBI:68478 |
| Type | chemical |
| Relations | 1 |
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Relations
| Regulator | Mechanism | target | score ℹ | |
|---|---|---|---|---|
| + | everolimus | down-regulates 
chemical inhibition
|
MTOR | 0.8 |
| Publications: | 1 | Organism: | Homo Sapiens | |