| + |
lurasidone | up-regulates activity 
chemical activation
|
HTR1A |
0.8 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-257839 |
|
|
Cricetulus longicaudatus |
|
| pmid |
sentence |
| 20404009 |
In vitro functional assays demonstrated that lurasidone acts as an antagonist at D2 and 5-HT7 receptors and as a partial agonist at the 5-HT1A receptor subtype. |
|
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-259463 |
|
|
Cricetulus longicaudatus |
|
| pmid |
sentence |
| 20404009 |
In vitro functional assays demonstrated that lurasidone acts as an antagonist at D2 and 5-HT7 receptors and as a partial agonist at the 5-HT1A receptor subtype. |
|
| Publications: |
2 |
Organism: |
Cricetulus Longicaudatus |
| + |
lurasidone | down-regulates activity 
chemical inhibition
|
HTR7 |
0.8 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-257840 |
|
|
Cricetulus longicaudatus |
CHO Cell |
| pmid |
sentence |
| 20404009 |
In vitro functional assays demonstrated that lurasidone acts as an antagonist at D2 and 5-HT7 receptors and as a partial agonist at the 5-HT1A receptor subtype. |
|
| Publications: |
1 |
Organism: |
Cricetulus Longicaudatus |
| + |
lurasidone | down-regulates activity
chemical inhibition
|
ADRA2A |
0.8 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-257842 |
|
|
Cricetulus longicaudatus |
CHO Cell |
| pmid |
sentence |
| 20404009 |
Lurasidone was found to have potent binding affinity for dopamine D2, 5-hydroxytryptamine 2A (5-HT2A), 5-HT7, 5-HT1A, and noradrenaline 2C receptors. |
|
| Publications: |
1 |
Organism: |
Cricetulus Longicaudatus |
| + |
lurasidone | down-regulates activity
chemical inhibition
|
HTR2A |
0.8 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-259465 |
|
|
Cricetulus longicaudatus |
|
| pmid |
sentence |
| 20404009 |
Lurasidone was found to have potent binding affinity for dopamine D2, 5-hydroxytryptamine 2A (5-HT2A), 5-HT7, 5-HT1A, and noradrenaline 2C receptors. |
|
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-257841 |
|
|
Cricetulus longicaudatus |
|
| pmid |
sentence |
| 20404009 |
Lurasidone was found to have potent binding affinity for dopamine D2, 5-hydroxytryptamine 2A (5-HT2A), 5-HT7, 5-HT1A, and noradrenaline 2C receptors. |
|
| Publications: |
2 |
Organism: |
Cricetulus Longicaudatus |
| + |
lurasidone | down-regulates activity
chemical inhibition
|
ADRA2C |
0.8 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-257837 |
|
|
Cricetulus longicaudatus |
CHO Cell |
| pmid |
sentence |
| 20404009 |
Lurasidone was found to have potent binding affinity for dopamine D2, 5-hydroxytryptamine 2A (5-HT2A), 5-HT7, 5-HT1A, and noradrenaline 2C receptors. |
|
| Publications: |
1 |
Organism: |
Cricetulus Longicaudatus |
| + |
lurasidone | down-regulates activity
chemical inhibition
|
DRD2 |
0.8 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-259462 |
|
|
Cricetulus longicaudatus |
|
| pmid |
sentence |
| 20404009 |
In vitro functional assays demonstrated that lurasidone acts as an antagonist at D2 and 5-HT7 receptors and as a partial agonist at the 5-HT1A receptor subtype. |
|
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-257838 |
|
|
Cricetulus longicaudatus |
|
| pmid |
sentence |
| 20404009 |
In vitro functional assays demonstrated that lurasidone acts as an antagonist at D2 and 5-HT7 receptors and as a partial agonist at the 5-HT1A receptor subtype. |
|
| Publications: |
2 |
Organism: |
Cricetulus Longicaudatus |
3.0
lurasidone
