Summary

Name SRGAP3
Full Name SLIT-ROBO Rho GTPase-activating protein 3
Synonyms srGAP3, Mental disorder-associated GAP, Rho GTPase-activating protein 14, WAVE-associated Rac GTPase-activating protein, WRP | ARHGAP14, KIAA0411, KIAA1156, MEGAP, SRGAP2
Primary ID O43295
Links - -
Type protein
Relations 5
Function GTPase-activating protein for RAC1 and perhaps Cdc42, but not for RhoA small GTPase. May attenuate RAC1 signaling in neurons.

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Relations

Regulator Mechanism target score ℹ
+ SRGAP3down-regulates img/indirect_inhibition.png RAC2 0.533
Publications: 1 Organism: Homo Sapiens
+ SRGAP3up-regulates img/direct-activation.png binding WASF1 0.57
Publications: 1 Organism: Homo Sapiens
+ SRGAP3down-regulates img/indirect_inhibition.png RAC3 0.538
Publications: 1 Organism: Homo Sapiens
+ SRGAP3down-regulates img/indirect_inhibition.png RAC1 0.547
Publications: 1 Organism: Homo Sapiens
+ SRGAP3down-regulates activity img/direct_inhibition.png gtpase-activating protein RAC1 0.547
Publications: 1 Organism: Homo Sapiens