3.0
Summary
| Name |  TNFSF12
|
| Full Name | Tumor necrosis factor ligand superfamily member 12 |
| Synonyms | APO3 ligand, TNF-related weak inducer of apoptosis, TWEAK | APO3L, DR3LG |
| Primary ID | O43508 |
| Links |  -  -  |
| Type | protein |
| Relations | 1 |
| Function | Binds to FN14 and possibly also to TNRFSF12/APO3. Weak inducer of apoptosis in some cell types. Mediates NF-kappa-B activation. Promotes angiogenesis and the proliferation of endothelial cells. Also involved in induction of inflammatory cytokines. Promotes IL8 secretion. |
polyubiquitination