| + |
TNFSF12 | down-regulates quantity by destabilization 
polyubiquitination
|
MYH3 |
0.2 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-272628 |
|
|
Mus musculus |
C2C12 Cell |
| pmid |
sentence |
| 17314137 |
TWEAK induces ubiquitination of MyHCf and expression of atrogin-1 and MuRF1 in myotubes. our data show that TWEAK rapidly increases the conjugation of ubiquitin to MyHCf (Fig. 3A) and ubiquitination preceded the degradation of MyHCf (Fig. 2C and Fig. 3A). |
|
| Publications: |
1 |
Organism: |
Mus Musculus |
| + |
MYOD1/SWI/SNF complex | up-regulates quantity by expression 
transcriptional regulation
|
MYH3 |
0.462 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-136647 |
|
|
Homo sapiens |
|
| pmid |
sentence |
| 15870273 |
Swi/snf enzymes are necessary for myod to activate muscle gene transcription / myod increased the expression of 94 genes and decreased that of 70 genes /these 94 genes (represented by 96 array features) were analyzed for their dependence on a functional brg1-based swi/snf complex. In the presence of dominant-negative brg1, 29 genes did not achieve full activation by myod, as determined by statistical criteria (q 0.05) and a twofold or more decrease in expression level (table 1; see also table s1 in the supplemental material) |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
| Tissue: |
Muscle |
3.0
MYH3
- 
- 