3.0
Summary
| Name |  HBP1View Modifications |
| Full Name | HMG box-containing protein 1 |
| Synonyms | HMG box transcription factor 1, High mobility group box transcription factor 1 |
| Primary ID | O60381 |
| Links |  -  -  |
| Type | protein |
| Relations | 5 |
| Function | Transcriptional repressor that binds to the promoter region of target genes. Plays a role in the regulation of the cell cycle and of the Wnt pathway. Binds preferentially to the sequence 5'-TTCATTCATTCA-3'. Binding to the histone H1.0 promoter is enhanced by interaction with RB1. Disrupts the interaction between DNA and TCF4. |
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Modifications Tables
Relations
| Regulator | Mechanism | target | score ℹ | |
|---|---|---|---|---|
| + | PIM1 | up-regulates activity 
phosphorylation
|
HBP1 | 0.2 |
| Publications: | 2 | Organism: | Homo Sapiens | |
| + | MAPK11 | up-regulates
phosphorylation
|
HBP1 | 0.403 |
| Publications: | 1 | Organism: | Homo Sapiens | |
| + | MAPK14 | up-regulates
phosphorylation
|
HBP1 | 0.404 |
| Publications: | 1 | Organism: | Homo Sapiens | |
| + | HBP1 | down-regulates quantity by repression 
transcriptional regulation
|
NCF1 | 0.268 |
| Publications: | 1 | Organism: | Homo Sapiens | |