3.0
Summary
| Name |  SBF1
|
| Full Name | Myotubularin-related protein 5 |
| Synonyms | SET-binding factor 1, Sbf1 | MTMR5 |
| Primary ID | O95248 |
| Links |  -  -  |
| Type | protein |
| Relations | 2 |
| Function | Acts as an adapter for the phosphatase MTMR2 to regulate MTMR2 catalytic activity and subcellular location (PubMed:12668758). May function as a guanine nucleotide exchange factor (GEF) activating RAB28 (PubMed:20937701). Promotes the exchange of GDP to GTP, converting inactive GDP-bound Rab proteins into their active GTP-bound form (PubMed:20937701). Inhibits myoblast differentiation in vitro and induces oncogenic transformation in fibroblasts (PubMed:9537414). |
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