3.0
Summary
| Name |  MTMR2
|
| Full Name | Myotubularin-related protein 2 |
| Synonyms | Phosphatidylinositol-3,5-bisphosphate 3-phosphatase, 3.1.3.95, Phosphatidylinositol-3-phosphate phosphatase, 3.1.3.64 | KIAA1073 |
| Primary ID | Q13614 |
| Links |  -  -  |
| Type | protein |
| Relations | 3 |
| Function | Phosphatase that acts on lipids with a phosphoinositol headgroup. Has phosphatase activity towards phosphatidylinositol 3-phosphate and phosphatidylinositol 3,5-bisphosphate (PubMed:11733541, PubMed:12668758, PubMed:21372139, PubMed:14690594). Binds phosphatidylinositol 4-phosphate, phosphatidylinositol 5-phosphate, phosphatidylinositol 3,5-bisphosphate and phosphatidylinositol 3,4,5-trisphosphate (By similarity). Stabilizes SBF2/MTMR13 at the membranes (By similarity). Specifically in peripheral nerves, stabilizes SBF2/MTMR13 protein (By similarity). |
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Relations
| Regulator | Mechanism | target | score ℹ | |
|---|---|---|---|---|
| + | MTMR2 | down-regulates quantity 
chemical modification
|
1-phosphatidyl-1D-myo-inositol 3-phosphate(3-) | 0.8 |
| Publications: | 1 | Organism: | Homo Sapiens | |
| + | SBF1 | up-regulates activity 
binding
|
MTMR2 | 0.616 |
| Publications: | 1 | Organism: | Chlorocebus Aethiops | |
| + | MTMR2 | up-regulates quantity
chemical modification
|
1-phosphatidyl-1D-myo-inositol(1-) | 0.8 |
| Publications: | 1 | Organism: | Homo Sapiens | |