3.0
Summary
| Name |  LTA
|
| Full Name | Lymphotoxin-alpha |
| Synonyms | LT-alpha, TNF-beta, Tumor necrosis factor ligand superfamily member 1 | TNFB, TNFSF1 |
| Primary ID | P01374 |
| Links |  -  -  |
| Type | protein |
| Relations | 1 |
| Function | Cytokine that in its homotrimeric form binds to TNFRSF1A/TNFR1, TNFRSF1B/TNFBR and TNFRSF14/HVEM (PubMed:9462508). In its heterotrimeric form with LTB binds to TNFRSF3/LTBR. Lymphotoxin is produced by lymphocytes and is cytotoxic for a wide range of tumor cells in vitro and in vivo. |
binding